T-Mobile was founded in Germany July 1993 to provide mobile telephony services in Germany. Since then, the company has developed into an integrated and coordinated global brand, and one of the leading international mobile communications carriers. T-Mobile operates in key markets in Europe, including Austria, Czech Republic, Germany, the Netherlands, and the United Kingdom, as well as in the United States. By the end of 2006, T-Mobile International employed over 54,000 people serving more than 106.4 million customers in the twelve T-Mobile markets.

The U.S. Department of Defense, through its Defense Information Systems Agency, established a central metadata registry, to provide XML components approved for DoD software development, as well as reference data tables and codes, such as country and state codes. The registry provides an authoritative resource for DoD software architects and developers, and is based ebXML Registry and Repository standard.

The Public Health Information Network Messaging System (PHINMS) provides a secure and reliable messaging system for the Public Health Information Network. The Centers for Disease Control and Prevention (CDC) say that there are currently multiple systems in place that support communications for public health labs, the clinical community, and state and local health departments. However, many of these systems operate in isolation, not capitalizing on the potential for a cross-fertilization of data exchange.

Norway's National Insurance Administration (NIA) upgraded the EDI-based communications infrastructure it used to connect to its business partners with a new architecture based on open standards, including the ebXML Messaging OASIS Standard, ISO 15000-2. NIA's ebXML Message service was built using the Xenos terminalONE end-to-end, transaction gateway solution.

Helena Chemical Company, a leading U.S. agricultural products specialist, used BPEL (Business Process Execution Language) and ebXML B2B technologies together to automate better and more productive supplier/distributor relationships.